Association of human leukocyte antigen with interstitial lung disease in rheumatoid arthritis: a protective role for shared epitope.

INTRODUCTION: Interstitial Lung Disease (ILD) is frequently associated with Rheumatoid Arthritis (RA) as one of extra-articular manifestations. Many studies for Human Leukocyte Antigen (HLA) allelic association with RA have been reported, but few have been validated in an RA subpopulation with ILD....

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Main Authors: Hiroshi Furukawa, Shomi Oka, Kota Shimada, Shoji Sugii, Jun Ohashi, Toshihiro Matsui, Tatsuoh Ikenaka, Hisanori Nakayama, Atsushi Hashimoto, Hirokazu Takaoka, Yoshiyuki Arinuma, Yuko Okazaki, Hidekazu Futami, Akiko Komiya, Naoshi Fukui, Tadashi Nakamura, Kiyoshi Migita, Akiko Suda, Shouhei Nagaoka, Naoyuki Tsuchiya, Shigeto Tohma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3346749?pdf=render