Insulin modulates the frequency of Ca2+ oscillations in mouse pancreatic islets.

Pancreatic islets can adapt to oscillatory glucose to produce synchronous insulin pulses. Can islets adapt to other oscillatory stimuli, specifically insulin? To answer this question, we stimulated islets with pulses of exogenous insulin and measured their Ca2+ oscillations. We observed that suffici...

Full description

Bibliographic Details
Main Authors: Boah Lee, Taegeun Song, Kayoung Lee, Jaeyoon Kim, Per-Olof Berggren, Sung Ho Ryu, Junghyo Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5573301?pdf=render