Gene expression changes in sickle cell reticulocytes and their clinical associations

Gene expression changes in sickle cell reticulocytes and their clinical associations

Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression chang...

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Bibliografiske detaljer
Main Authors: Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Format: Article
Sprog:English
Udgivet: Nature Portfolio 2023-08-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-023-40039-2

Internet

https://doi.org/10.1038/s41598-023-40039-2

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