Gene expression changes in sickle cell reticulocytes and their clinical associations
Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression chang...
Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Nature Portfolio
2023-08-01
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Σειρά: | Scientific Reports |
Διαθέσιμο Online: | https://doi.org/10.1038/s41598-023-40039-2 |