Gene expression changes in sickle cell reticulocytes and their clinical associations

Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression chang...

Полное описание

Библиографические подробности
Главные авторы: Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2023-08-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-023-40039-2