OPEN QUESTIONS IN ORIGIN OF LIFE: EXPERIMENTAL STUDIES ON THE ORIGIN OF NUCLEIC ACIDS AND PROTEINS WITH SPECIFIC AND FUNCTIONAL SEQUENCES BY A CHEMICAL SYNTHETIC BIOLOGY APPROACH

OPEN QUESTIONS IN ORIGIN OF LIFE: EXPERIMENTAL STUDIES ON THE ORIGIN OF NUCLEIC ACIDS AND PROTEINS WITH SPECIFIC AND FUNCTIONAL SEQUENCES BY A CHEMICAL SYNTHETIC BIOLOGY APPROACH

In this mini-review we present some experimental approaches to the important issue in the origin of life, namely the origin of nucleic acids and proteins with specific and functional sequences. The formation of macromolecules on prebiotic Earth faces practical and conceptual difficulties. From the c...

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Bibliographic Details
Main Authors: Katarzyna Adamala, Fabrizio Anella, Rafal Wieczorek, Pasquale Stano, Cristiano Chiarabelli, Pier Luigi Luisi
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Computational and Structural Biotechnology Journal
Subjects:
fragment condensation
organocatalysis
origin of life
random proteins
random RNA
sequence space
Ser-His
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014600076

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http://www.sciencedirect.com/science/article/pii/S2001037014600076

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