Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity

Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity

Sevoflurane, a volatile anesthetic, is known to induce widespread neuronal degeneration and apoptosis. Recently, the stress-inducible protein sestrin 2 and adenosine monophosphate-activated protein kinase (AMPK) have been found to regulate the levels of intracellular reactive oxygen species (ROS) an...

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Bibliographic Details
Main Authors: Zhang Yibing, Zhao Yong, Ran Yongwang, Guo Jianyou, Cui Haifeng, Liu Sha
Format: Article
Language:English
Published: De Gruyter 2020-06-01
Series:Translational Neuroscience
Subjects:
5′-amp-activated protein kinase
neurotoxicity
notoginsenoside r1
sevoflurane
sestrin-2
reactive oxygen species
Online Access:https://doi.org/10.1515/tnsci-2020-0118

Internet

https://doi.org/10.1515/tnsci-2020-0118

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