Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases

Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases

Background: Pulmonary hypertension (PH) is a life-threatening complication of connective tissue diseases (CTD); in this study, we aimed at investigating the potential role of inducible co-stimulator (ICOS) and its ligand (ICOS-L) as biomarkers of PH in CTD. Materials and Methods: We recruited 109 pa...

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Bibliographic Details
Main Authors: Mattia Bellan, Francesco Murano, Federico Ceruti, Cristina Piccinino, Stelvio Tonello, Rosalba Minisini, Ailia Giubertoni, Daniele Sola, Roberta Pedrazzoli, Veronica Maglione, Giulia Francesca Manfredi, Antonio Acquaviva, Roberto Piffero, Giuseppe Patti, Mario Pirisi, Pier Paolo Sainaghi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Diagnostics
Subjects:
ICOS
ICOSL
pulmonary arterial hypertension
systemic sclerosis
connective tissue diseases
Online Access:https://www.mdpi.com/2075-4418/12/3/704

Internet

https://www.mdpi.com/2075-4418/12/3/704

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