The hyperinsulinemia produced by concanavalin A in rats is opioid-dependent and hormonally regulated
The present study examines the effect of concanavalin A (Con A) on the blood insulin and glucose levels of rats. Male and female rats treated with Con A (62.5-500 µg/kg) for three days showed a dose- and time-dependent hyperinsulinemia that lasted more than 48 h. Male rats were more sensitive to Con...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
1998-05-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000500015 |