The hyperinsulinemia produced by concanavalin A in rats is opioid-dependent and hormonally regulated

The hyperinsulinemia produced by concanavalin A in rats is opioid-dependent and hormonally regulated

The present study examines the effect of concanavalin A (Con A) on the blood insulin and glucose levels of rats. Male and female rats treated with Con A (62.5-500 µg/kg) for three days showed a dose- and time-dependent hyperinsulinemia that lasted more than 48 h. Male rats were more sensitive to Con...

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Bibliographic Details
Main Authors:	J. Francisco-DoPrado, J.E. Zambelli, M.H. Melo-Lima, G. Ribeiro-DaSilva
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 1998-05-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	concanavalin A hyperinsulinemia blood glucose alterations sex hormones endogenous opioids canatoxin
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000500015

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