Design and Evaluation of Orally Dispersible Tablets Containing Amlodipine Inclusion Complexes in Hydroxypropyl-β-cyclodextrin and Methyl-β-cyclodextrin

Design and Evaluation of Orally Dispersible Tablets Containing Amlodipine Inclusion Complexes in Hydroxypropyl-β-cyclodextrin and Methyl-β-cyclodextrin

The development of new orally dispersible tablets containing amlodipine (AML) inclusion complexes in hydroxypropyl-β-cyclodextrin (HP-β-CD) and in methyl-β-cyclodextrin (Me-β-CD) was studied. The methods of obtaining amlodipine and the physical and chemical properties of the inclusion complexes usin...

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Bibliographic Details
Main Authors: Marian Novac, Adina Magdalena Musuc, Emma Adriana Ozon, Iulian Sarbu, Mirela Adriana Mitu, Adriana Rusu, Simona Petrescu, Irina Atkinson, Daniela Gheorghe, Dumitru Lupuliasa
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Materials
Subjects:
amlodipine besylate
hydroxypropyl-β-cyclodextrin
methyl-β-cyclodextrin
lyophilization technique
Online Access:https://www.mdpi.com/1996-1944/15/15/5217

Internet

https://www.mdpi.com/1996-1944/15/15/5217

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