Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma

Chromosome Instability (CIN) in tumors affects carcinogenesis, drug resistance, and recurrence/prognosis. Thus, it has a high impact on outcomes in clinic. However, how CIN occurs in human tumors remains elusive. Although cells with CIN (i.e., pre/early cancer cells) are proposed to be removed by ap...

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Bibliographic Details
Main Authors: Chinthalapally V. Rao, Chao Xu, Mudassir Farooqui, Yuting Zhang, Adam S. Asch, Hiroshi Y. Yamada
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/11/2586