Sensing the Messenger: Potential Roles of Cyclic-di-GMP in Rickettsial Pathogenesis

Pathogenic bacteria causing human rickettsioses, transmitted in nature by arthropod vectors, primarily infect vascular endothelial cells lining the blood vessels, resulting in ‘endothelial activation’ and onset of innate immune responses. Nucleotide second messengers are long presumed to be the stim...

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Bibliographic Details
Main Authors: Hema P. Narra, Abha Sahni, Krishna Mohan Sepuru, Jessica Alsing, Sanjeev K. Sahni
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/7/3853