Identification of candidate genes and mutations in QTL regions for chicken growth using bioinformatic analysis of NGS and SNP-chip data

Identification of candidate genes and mutations in QTL regions for chicken growth using bioinformatic analysis of NGS and SNP-chip data

Mapping of chromosomal regions harboring genetic polymorphisms that regulate complex traits is usually followed by a search for the causative mutations underlying the observed effects. This is often a challenging task even after fine mapping, as millions of base pairs including many genes will typic...

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Bibliographic Details
Main Authors: Muhammad eAhsan, Xidan eLi, Andreas E Lundberg, Marcin eKierczak, Paul B Siegel, Örjan eCarlborg, Stefan eMarklund
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Genetics
Subjects:
Growth
SNP
Resequencing
QTL
candidate genes
functional prediction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00226/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00226/full

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