β Cell GHS-R Regulates Insulin Secretion and Sensitivity

β Cell GHS-R Regulates Insulin Secretion and Sensitivity

Growth hormone secretagogue receptor (GHS-R) is widely known to regulate food intake and adiposity, but its role in glucose homeostasis is unclear. In this study, we investigated the expression of GHS-R in mouse pancreatic islets and its role in glycemic regulation. We used Ghsr-IRES-tauGFP mice, wi...

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Bibliographic Details
Main Authors: Geetali Pradhan, Chia-Shan Wu, Daniel Villarreal, Jong Han Lee, Hye Won Han, Akhilesh Gaharwar, Yanan Tian, Wenxian Fu, Shaodong Guo, Roy G. Smith, Yuxiang Sun
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
growth hormone secretagogue receptor (GHS-R)
glucose-stimulated insulin secretion (GSIS)
MIP-Cre/ERT
pancreatic islets
β cells
insulin secretion
Online Access:https://www.mdpi.com/1422-0067/22/8/3950

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https://www.mdpi.com/1422-0067/22/8/3950

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