Antidiabetic Activity of a Flavonoid-Rich Extract From Sophora davidii (Franch.) Skeels in KK-Ay Mice via Activation of AMP-Activated Protein Kinase

Antidiabetic Activity of a Flavonoid-Rich Extract From Sophora davidii (Franch.) Skeels in KK-Ay Mice via Activation of AMP-Activated Protein Kinase

The present study was undertaken to investigate the hypoglycemic activity and potential mechanisms of action of a flavonoid-rich extract from Sophora davidii (Franch.) Skeels (SD-FRE) through in vitro and in vivo studies. Four main flavonoids of SD-FRE namely apigenin, maackiain, leachianone A and l...

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Bibliographic Details
Main Authors: Yun Huang, Ji Hao, Di Tian, Yanzhang Wen, Ping Zhao, Hao Chen, Yibin Lv, Xinzhou Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
antidiabetic
Sophora davidii (Franch.) Skeels
KK-Ay mice
GLUT4
AMPK
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00760/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00760/full

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