Heterologous DNA Prime- Subunit Protein Boost with Chikungunya Virus E2 Induces Neutralizing Antibodies and Cellular-Mediated Immunity

Heterologous DNA Prime- Subunit Protein Boost with Chikungunya Virus E2 Induces Neutralizing Antibodies and Cellular-Mediated Immunity

Chikungunya virus (CHIKV) has become a significant public health concern due to the increasing number of outbreaks worldwide and the associated comorbidities. Despite substantial efforts, there is no specific treatment or licensed vaccine against CHIKV to date. The E2 glycoprotein of CHIKV is a prom...

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Bibliographic Details
Main Authors: Fernanda Caroline Coirada, Edgar Ruz Fernandes, Lucas Rodrigues de Mello, Viviane Schuch, Gúbio Soares Campos, Carla Torres Braconi, Silvia Beatriz Boscardin, Daniela Santoro Rosa
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
CHIKV
envelope
heterologous prime-boost
adjuvants
DNA vaccine
single chain
Online Access:https://www.mdpi.com/1422-0067/24/13/10517

Internet

https://www.mdpi.com/1422-0067/24/13/10517

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