LXR agonism for CNS diseases: promises and challenges

LXR agonism for CNS diseases: promises and challenges

Abstract The unfavorable prognosis of many neurological conditions could be attributed to limited tissue regeneration in central nervous system (CNS) and overwhelming inflammation, while liver X receptor (LXR) may regulate both processes due to its pivotal role in cholesterol metabolism and inflamma...

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Bibliographic Details
Main Authors: Ruiyi Zhang, Emily Wuerch, V. Wee Yong, Mengzhou Xue
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Neuroinflammation
Subjects:
Liver X receptor
Neurological diseases
Neuroinflammation
Cholesterol metabolism
Tissue regeneration
Clinical translation
Online Access:https://doi.org/10.1186/s12974-024-03056-0

Internet

https://doi.org/10.1186/s12974-024-03056-0

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