LXR agonism for CNS diseases: promises and challenges

LXR agonism for CNS diseases: promises and challenges

Abstract The unfavorable prognosis of many neurological conditions could be attributed to limited tissue regeneration in central nervous system (CNS) and overwhelming inflammation, while liver X receptor (LXR) may regulate both processes due to its pivotal role in cholesterol metabolism and inflamma...

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Bibliographic Details
Main Authors:	Ruiyi Zhang, Emily Wuerch, V. Wee Yong, Mengzhou Xue
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Series:	Journal of Neuroinflammation
Subjects:	Liver X receptor Neurological diseases Neuroinflammation Cholesterol metabolism Tissue regeneration Clinical translation
Online Access:	https://doi.org/10.1186/s12974-024-03056-0

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