Redox-dependent loss of flavin by mitochondria complex I is different in brain and heart

Redox-dependent loss of flavin by mitochondria complex I is different in brain and heart

Pathologies associated with tissue ischemia/reperfusion (I/R) in highly metabolizing organs such as the brain and heart are leading causes of death and disability in humans. Molecular mechanisms underlying mitochondrial dysfunction during acute injury in I/R are tissue-specific, but their details ar...

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Bibliographic Details
Main Authors: Belem Yoval-Sánchez, Fariha Ansari, Joel James, Zoya Niatsetskaya, Sergey Sosunov, Peter Filipenko, Irina G. Tikhonova, Vadim Ten, Ilka Wittig, Ruslan Rafikov, Alexander Galkin
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Redox Biology
Subjects:
Mitochondrial complex I
Flavin mononucleotide
Reverse electron transfer
Heart
Brain
Tissue-specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722000301

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http://www.sciencedirect.com/science/article/pii/S2213231722000301

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