Impairment of Glucose Metabolism and Suppression of Stemness in MCF-7/SC Human Breast Cancer Stem Cells by Nootkatone

Impairment of Glucose Metabolism and Suppression of Stemness in MCF-7/SC Human Breast Cancer Stem Cells by Nootkatone

Targeting cancer stem cell metabolism has emerged as a promising therapeutic strategy for cancer treatment. Breast cancer stem cells (BCSCs) exert distinct metabolism machinery, which plays a major role in radiation and multidrug resistance. Therefore, exploring the mechanisms involved in energy uti...

Full description

Bibliographic Details
Main Authors: Yen Thi-Kim Nguyen, Ngoc Bao To, Vi Nguyen-Phuong Truong, Hee Young Kim, Meran Keshawa Ediriweera, Yoongho Lim, Somi Kim Cho
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
breast cancer stem cells
glycolysis
oxidative phosphorylation
cancer metabolism
nootkatone
AMPK
Online Access:https://www.mdpi.com/1999-4923/14/5/906

Internet

https://www.mdpi.com/1999-4923/14/5/906

Similar Items