Eradication of CD48-positive tumors by selectively enhanced YTS cells harnessing the lncRNA NeST

Summary: Natural killer (NK) cells are currently used in clinical trials to treat tumors. However, such therapies still suffer from problems such as donor variability, reproducibility, and more, which prevent a wider use of NK cells therapeutics. Here we show a potential immunotherapy combining NK c...

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Bibliographic Details
Main Authors: Rebecca Kotzur, Natan Stein, Shira Kahlon, Orit Berhani, Batya Isaacson, Ofer Mandelboim
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223013615