Chemometrically Assisted Optimization of Pregabalin Fluorescent Derivatization Reaction with a Novel Xanthone Analogue and Validation of the Method for the Determination of Pregabalin in Bulk via a Plate Reader

Chemometrically Assisted Optimization of Pregabalin Fluorescent Derivatization Reaction with a Novel Xanthone Analogue and Validation of the Method for the Determination of Pregabalin in Bulk via a Plate Reader

Quantitation of chromophore-free analytes is always a challenge. To this purpose, derivatization of the analyte constitutes a common strategy, leading to a product with a strong signal. In the current study, a novel xanthone analogue was utilized for the first time for the derivatization of pregabal...

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Bibliographic Details
Main Authors: Nikolaos Kritikos, Aikaterini Iliou, Amalia D. Kalampaliki, Evangelos Gikas, Ioannis K. Kostakis, Benoît Y. Michel, Yannis Dotsikas
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
fluorescence
xanthone
derivatization reaction
plate reader
pregabalin
experimental design
Online Access:https://www.mdpi.com/1420-3049/27/6/1954

Internet

https://www.mdpi.com/1420-3049/27/6/1954

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