Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses.

EtOH extracts from the leaves and twigs of Nectandra oppositifolia Nees & Mart. shown activity against amastigote forms of Trypanosoma cruzi. These extracts were subjected to successive liquid-liquid partitioning to afford bioactive CH2Cl2 fractions. UHPLC-TOF-HRMS/MS and molecular networking we...

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Main Authors: Geanne A Alves Conserva, Luis M Quirós-Guerrero, Thais A Costa-Silva, Laurence Marcourt, Erika G Pinto, Andre G Tempone, João Paulo S Fernandes, Jean-Luc Wolfender, Emerson F Queiroz, João Henrique G Lago
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247334