Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines

Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines

Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage to mitochondria, leading to the impairment of metabolic functions and apoptosis. In this work, for the first time, we investigated the effects of photoexcited thioridazine (T...

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Bibliographic Details
Main Authors: T. Rodrigues, P.A.F. Faria, F.S. Pessoto, C.G. Santos, I.L. Nantes
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2005-01-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
trifluoperazine, thioridazine, fluphenazine, rat liver mitochondria, oxidative stress, photochemistry, photodamage, respiratory chain
Online Access:http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/607

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http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/607

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