Single-molecule measurements of bacteriophage lambda DNA packaging using purified terminase motor proteins and E. coli integration host factor

Single-molecule measurements of bacteriophage lambda DNA packaging using purified terminase motor proteins and E. coli integration host factor

Abstract Biomotor-driven DNA packaging is a key step in the life cycle of many viruses. We previously developed single-molecule methods using optical tweezers to measure packaging dynamics of the bacteriophage lambda motor. The lambda system is more complex than others examined via single-molecule a...

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Bibliographic Details
Main Authors: Brandon Rawson, Qin Yang, Carlos E. Catalano, Douglas E. Smith
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Molecular motor
Viral DNA packaging
Optical tweezers
Single-molecule biophysics
Terminase holoenzyme
Online Access:https://doi.org/10.1038/s41598-024-74915-2

Internet

https://doi.org/10.1038/s41598-024-74915-2

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