INCREASED FORMATION OF PHOSPHORYLATED H2AX FOCI IN NUCLEI OF CELLS INFECTED BY HEPATITIS B AND B+D VIRUSES

INCREASED FORMATION OF PHOSPHORYLATED H2AX FOCI IN NUCLEI OF CELLS INFECTED BY HEPATITIS B AND B+D VIRUSES

Liver cirrhosis and hepatocellular carcinoma are the most common outcomes of chronic hepatitis B. Hepatitis B virus (HBV) induces transformation and cell death in chronic hepatitis B (CHB). DNA double strand breaks (DSBs) represent the most dangerous type of genome damage. It was shown previously th...

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Bibliographic Details
Main Authors: D. S. Kostyushev, S. A. Brezgin, A. P. Kostyusheva, A. D. Lipatnikov, V. N. Simirskii, N. A. Mamonova, E. V. Volchkova, V. V. Maleyev, V. P. Chulanov
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2018-08-01
Series:Вопросы вирусологии
Subjects:
yh2ax
hepatitis b virus
hepatitis d virus
double strand breaks
genome damage
hepatocytes
hepatoma cells
Online Access:https://virusjour.crie.ru/jour/article/viewFile/202/112

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https://virusjour.crie.ru/jour/article/viewFile/202/112

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