Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects
Abstract Background In a standard two-stage SMART design, the intermediate response to the first-stage intervention is measured at a fixed time point for all participants. Subsequently, responders and non-responders are re-randomized and the final outcome of interest is measured at the end of the st...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-08-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12874-016-0202-7 |