Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?

<p>Abstract</p> <p>Background</p> <p>A novel member of the Wnt signalling pathway, Chibby, was recently identified. This protein inhibits Wnt/β-catenin mediated transcriptional activation by competing with Lef-1 (the transcription factor and target of β-catenin) to bind...

Full description

Bibliographic Details
Main Authors: Beaune Philippe, Berger Anne, Goasguen Nicolas, Lièvre Astrid, Teboul David, Gad Sophie, Laurent-Puig Pierre
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/4/31