The Effect of Aging on Nitric Oxide Production during Cerebral Ischemia and Reperfusion in Wistar Rats and Spontaneous Hypertensive Rats: An In Vivo Microdialysis Study

The Effect of Aging on Nitric Oxide Production during Cerebral Ischemia and Reperfusion in Wistar Rats and Spontaneous Hypertensive Rats: An In Vivo Microdialysis Study

Nitric oxide (NO) is involved in the pathogenesis of cerebral ischemic injury. Here, we investigated the effects of aging on NO production during cerebral ischemia-reperfusion (IR). Male Wister rats (WRs) were assigned to 12-month-old (older; <i>n</i> = 5) and 3-month-old (younger; <i...

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Bibliographic Details
Main Authors: Yasuo Ito, Harumitsu Nagoya, Masamizu Yamazato, Yoshio Asano, Masahiko Sawada, Tomokazu Shimazu, Makiko Hirayama, Toshimasa Yamamoto, Nobuo Araki
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
nitric oxide (NO)
in vivo microdialysis
forebrain ischemia
striatum
hippocampus
Online Access:https://www.mdpi.com/1422-0067/24/16/12749

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https://www.mdpi.com/1422-0067/24/16/12749

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