p-hydroxy benzaldehyde attenuates intestinal epithelial barrier dysfunction caused by colitis via activating the HNF-1β/SLC26A3 pathway

p-hydroxy benzaldehyde attenuates intestinal epithelial barrier dysfunction caused by colitis via activating the HNF-1β/SLC26A3 pathway

BackgroundIntestinal epithelial barrier dysfunction is intricately linked to the pathogenesis of ulcerative colitis (UC). Dietary interventions that bolster intestinal epithelial barrier function can effectively thwart UC onset. Our prior research revealed that p-Hydroxy benzaldehyde (HD), a phenoli...

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Bibliographic Details
Main Authors: Meng Liu, Yuhui Wang, Xiaotian Xu, Guoqiang Guan, Shu Zhang, Shengnan Zhu, Yang Liu, Yizhun Zhu, Xiaoqun Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
p-hydroxy benzaldehyde
intestinal epithelial barrier dysfunction
HNF-1β
SLC26A3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1448863/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1448863/full

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