Recombinant Poxvirus and the Tumor Microenvironment: Oncolysis, Immune Regulation and Immunization

Oncolytic viruses (OVs) are being extensively studied for their potential roles in the development of cancer therapy regimens. In addition to their direct lytic effects, OVs can initiate and drive systemic antitumor immunity indirectly via release of tumor antigen, as well as by encoding and deliver...

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Bibliographic Details
Main Authors: Daniel W. Sharp, Edmund C. Lattime
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/4/3/19