Preclinical Evaluation of F-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid Tumors

Preclinical Evaluation of F-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid Tumors

Purpose: We investigated 2-(5-fluoro-pentyl)-2-methyl-malonic acid ( 18 F-ML-10) positron emission tomography (PET) imaging of apoptosis posttherapy to determine optimal timing for predicting chemotherapy response in a mouse head/neck xenograft cancer model. Procedures: BALB/c nude mice (4-8 weeks o...

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Bibliographic Details
Main Authors: Emre Demirci MD, Rafay Ahmed MD, Meltem Ocak PhD, Joseph Latoche BS, April Radelet BS, Nicole DeBlasio BS, N. Scott Mason PhD, Carolyn J. Anderson PhD, James M. Mountz MD, PhD
Format: Article
Language:English
Published: SAGE Publications 2017-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012116685941

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https://doi.org/10.1177/1536012116685941

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