CIP2A induces PKM2 tetramer formation and oxidative phosphorylation in non-small cell lung cancer

Abstract Tumor cells are usually considered defective in mitochondrial respiration, but human non-small cell lung cancer (NSCLC) tumor tissues are shown to have enhanced glucose oxidation relative to adjacent benign lung. Here, we reported that oncoprotein cancerous inhibitor of protein phosphatase...

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Bibliographic Details
Main Authors: Li-Jun Liang, Fu-Ying Yang, Di Wang, Yan-Fei Zhang, Hong Yu, Zheng Wang, Bei-Bei Sun, Yu-Tao Liu, Gui-Zhen Wang, Guang-Biao Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00633-0