Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysis.

Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysis.

INTRODUCTION: SPARC is an important regulator of the extracellular matrix and has been suggested to improve delivery of albumin-bound cytotoxics. However, little is known regarding its role in breast cancer (BC). METHODS: We conducted a pooled analysis of publically available datasets, in which BC p...

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Bibliographic Details
Main Authors: Hatem A Azim, Sandeep Singhal, Michail Ignatiadis, Christine Desmedt, Debora Fumagalli, Isabelle Veys, Denis Larsimont, Martine Piccart, Stefan Michiels, Christos Sotiriou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637211?pdf=render

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http://europepmc.org/articles/PMC3637211?pdf=render

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