Amphotericin B-PEG Conjugates of ZnO Nanoparticles: Enhancement Antifungal Activity with Minimal Toxicity

Amphotericin B-PEG Conjugates of ZnO Nanoparticles: Enhancement Antifungal Activity with Minimal Toxicity

Amphotericin B (AMB) is commonly used to treat life-threatening systemic fungal infections. AMB formulations that are more efficient and less nephrotoxic are currently unmet needs. In the current study, new ZnO-PEGylated AMB (ZnO-AMB-PEG) nanoparticles (NPs) were synthesized and their antifungal eff...

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Detalles Bibliográficos
Autores principales: Saad M. Alshahrani, El-Sayed Khafagy, Yassine Riadi, Ahmed Al Saqr, Munerah M. Alfadhel, Wael A. H. Hegazy
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2022-08-01
Colección:Pharmaceutics
Materias:
amphotericin
PEGylation
ZnO
metallic nanoparticles
antifungal
Acceso en línea:https://www.mdpi.com/1999-4923/14/8/1646

Internet

https://www.mdpi.com/1999-4923/14/8/1646

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