Mechanisms of immunity in post-exposure vaccination against Ebola virus infection.

Ebolaviruses can cause severe hemorrhagic fever that is characterized by rapid viral replication, coagulopathy, inflammation, and high lethality rates. Although there is no clinically proven vaccine or treatment for Ebola virus infection, a virus-like particle (VLP) vaccine is effective in mice, gui...

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Bibliographic Details
Main Authors: Steven B Bradfute, Scott M Anthony, Kelly S Stuthman, Natarajan Ayithan, Prafullakumar Tailor, Carl I Shaia, Mike Bray, Keiko Ozato, Sina Bavari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364937?pdf=render