Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials

Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials

BackgroundThe cardiovascular effects of treating older adults with subclinical hypothyroidism (SCH) are uncertain. Although concerns have been raised regarding a potential increase in cardiovascular side effects from thyroid hormone replacement, undertreatment may also increase the risk of cardiovas...

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Bibliographic Details
Main Authors: Laurien E. Zijlstra, J. Wouter Jukema, Rudi G. J. Westendorp, Robert S. Du Puy, Rosalinde K. E. Poortvliet, Patricia M. Kearney, Linda O’Keeffe, Olaf M. Dekkers, Manuel R. Blum, Nicolas Rodondi, Tinh-Hai Collet, Terence J. Quinn, Naveed Sattar, David J. Stott, Stella Trompet, Wendy P. J. den Elzen, Jacobijn Gussekloo, Simon P. Mooijaart
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
cardiovascular disease
levothyroxine
randomised controlled trial
subclinical hypothyroidism
older adults
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.674841/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.674841/full

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