Epigenetic Reprogramming of CD4+ Helper T Cells as a Strategy to Improve Anticancer Immunotherapy

Epigenetic Reprogramming of CD4+ Helper T Cells as a Strategy to Improve Anticancer Immunotherapy

Evidences highlight the role of various CD4+ helper T cells (CD4+ Th) subpopulations in orchestrating the immune responses against cancers. Epigenetics takes an important part in the regulation of CD4+ Th polarization and plasticity. In this review, we described the epigenetic factors that govern CD...

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Bibliographic Details
Main Authors: Elodie Renaude, Marie Kroemer, Christophe Borg, Paul Peixoto, Eric Hervouet, Romain Loyon, Olivier Adotévi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
epigenetics
CD4+ helper T cells
plasticity
tumor microenvironment
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.669992/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.669992/full

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