Osthole Exhibits Anti-Cancer Property in Rat Glioma Cells Through Inhibiting PI3K/Akt and MAPK Signaling Pathways

Osthole Exhibits Anti-Cancer Property in Rat Glioma Cells Through Inhibiting PI3K/Akt and MAPK Signaling Pathways

Aims: The purpose of this study was to investigate how Osthole affects glioma cell proliferation, apoptosis, invasion and migration. Methods: Rat glioma cells were treated with different concentrations of Osthole (0 µM, 25 µM, 50 µM, and 100 µM). Cell proliferation was assessed by measuring PCNA exp...

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Bibliographic Details
Main Authors: Daofang Ding, Songpu Wei, Yi Song, Linghui Li, Guoqing Du, Hongsheng Zhan, Yuelong Cao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
PI3K/Akt
MAPK
Glioma cell
Proliferation
Apoptosis
Osthole
Online Access:http://www.karger.com/Article/FullText/356609

Internet

http://www.karger.com/Article/FullText/356609

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