Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability

Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability

Abstract Background The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more severe disease with poor survival prognosis in ma...

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Bibliographic Details
Main Authors: Olga Rafikova, Joel James, Cody A. Eccles, Sergey Kurdyukov, Maki Niihori, Mathews Valuparampil Varghese, Ruslan Rafikov
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Biology of Sex Differences
Subjects:
Pulmonary hypertension
Heme signaling
Lung permeability
Sex difference
Endothelial barrier function
Online Access:http://link.springer.com/article/10.1186/s13293-020-00289-5

Internet

http://link.springer.com/article/10.1186/s13293-020-00289-5

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