Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability
Abstract Background The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more severe disease with poor survival prognosis in ma...
Main Authors: | Olga Rafikova, Joel James, Cody A. Eccles, Sergey Kurdyukov, Maki Niihori, Mathews Valuparampil Varghese, Ruslan Rafikov |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Biology of Sex Differences |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13293-020-00289-5 |
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