The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

<p>Abstract</p> <p>Background</p> <p>Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells have a distinctive high frequency of sister chromatid excha...

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Bibliographic Details
Main Authors: Noonan James P, Yankiwski Victor, Neff Norma F
Format: Article
Language:English
Published: BMC 2001-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/2/11