Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques.

Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes are a valuable resource for cardiac therapeutic development; however, generation of these cells in large numbers and high purity is a limitation in widespread adoption. Here, design of experiments (DOE) is used to investigate the car...

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Bibliographic Details
Main Authors: Cassady E Rupert, Chinedu Irofuala, Kareen L K Coulombe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230001