Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects.
Endogenous retroviruses and retrotransposons contribute functional genetic variation in animal genomes. In mice, Intracisternal A Particles (IAPs) are a frequent source of both new mutations and polymorphism across laboratory strains. Intronic IAPs can induce alternative RNA processing choices, incl...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4383553?pdf=render |