Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects.

Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects.

Endogenous retroviruses and retrotransposons contribute functional genetic variation in animal genomes. In mice, Intracisternal A Particles (IAPs) are a frequent source of both new mutations and polymorphism across laboratory strains. Intronic IAPs can induce alternative RNA processing choices, incl...

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Bibliographic Details
Main Authors: Dorothy Concepcion, Kevin D Ross, Kasey R Hutt, Gene W Yeo, Bruce A Hamilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4383553?pdf=render

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