The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus.

Cross-resistance to insecticides in multiple resistant malaria vectors is hampering resistance management. Understanding its underlying molecular basis is critical to implementation of suitable insecticide-based interventions. Here, we established that the tandemly duplicated cytochrome P450s, CYP6P...

Full description

Bibliographic Details
Main Authors: Leon M J Mugenzi, Theofelix A Tekoh, Sulaiman S Ibrahim, Abdullahi Muhammad, Mersimine Kouamo, Murielle J Wondji, Helen Irving, Jack Hearn, Charles S Wondji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010678