Group I mGluR-Mediated Activation of Martinotti Cells Inhibits Local Cortical Circuitry in Human Cortex

Group I mGluR-Mediated Activation of Martinotti Cells Inhibits Local Cortical Circuitry in Human Cortex

Group I metabotropic glutamate receptors (mGluRs) mediate a range of signaling and plasticity processes in the brain and are of growing importance as potential therapeutic targets in clinical trials for neuropsychiatric and neurodevelopmental disorders (NDDs). Fundamental knowledge regarding the fun...

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Bibliographic Details
Main Authors: Tim Kroon, Julia Dawitz, Ioannis Kramvis, Jasper Anink, Joshua Obermayer, Matthijs B. Verhoog, René Wilbers, Natalia A. Goriounova, Sander Idema, Johannes C. Baayen, Eleonora Aronica, Huibert D. Mansvelder, Rhiannon M. Meredith
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mGluR
human cortex
Martinotti
fast-spiking interneuron
LTD
single-cell RNA-sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00315/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00315/full

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