Berbamine promotes macrophage autophagy to clear Mycobacterium tuberculosis by regulating the ROS/Ca2+ axis

Berbamine promotes macrophage autophagy to clear Mycobacterium tuberculosis by regulating the ROS/Ca2+ axis

ABSTRACT Drug-resistant tuberculosis (TB) poses a major threat to global TB control; consequently, there is an urgent need to develop novel anti-TB drugs or strategies. Host-directed therapy (HDT) is emerging as an effective treatment strategy, especially for drug-resistant TB. This study evaluated...

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Bibliographic Details
Main Authors: Su Zhang, Xuefeng Zhou, Min Ou, Xiangdong Fu, Qiao Lin, Xiaoyu Tao, Zhaoqin Wang, Aimei Liu, Guobao Li, Yuzhong Xu, Guoliang Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
Mycobacterium tuberculosis
berbamine
autophagy
ROS
calcium
Online Access:https://journals.asm.org/doi/10.1128/mbio.00272-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00272-23

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