Patient-derived xenograft models for gastrointestinal tumors: A single-center retrospective study

Patient-derived xenograft models for gastrointestinal tumors: A single-center retrospective study

BackgroundPatient-derived xenograft (PDX) models have shown a great efficiency in preclinical and translational applications. Gastrointestinal (GI) tumors have a strong heterogeneity, and the engraftment rate of PDX models remarkably vary. However, the clinicopathological and molecular characteristi...

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Bibliographic Details
Main Authors: Xiongfei Yu, Yiran Chen, Jun Lu, Kuifeng He, Yanyan Chen, Yongfeng Ding, Ketao Jin, Haiyong Wang, Haibin Zhang, Haohao Wang, Lisong Teng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
patient-derived xenograft model
gastrointestinal cancer
mutational status of RAS and BRAF
drug sensitivity
clinical transformation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.985154/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.985154/full

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